WebAug 27, 2006 · Nature Immunology - Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity Skip to main content Thank you for visiting nature.com. WebThe engagement of the CD40 and CD40 ligands, which are transiently expressed on T cells and other non-immune cells under inflammatory conditions, regulates a wide spectrum of …
National Center for Biotechnology Information
WebJun 20, 2024 · CD40L (CD154), a member of the tumor necrosis factor superfamily, is a co-stimulatory molecule that was first discovered on activated T cells. Beyond its fundamental role in adaptive immunity—ligation of CD40L to its receptor CD40 is a prerequisite for B cell activation and antibody production—evidence from more than two decades has … WebSep 27, 2024 · CD40 is a tumour necrosis factor receptor (TNFR) superfamily member expressed broadly on antigen-presenting cells (APCs), and controls a key immunostimulatory pathway required for humoral and ... how to make a car untowable
Humoral Immunity Pathway Medicine
WebFeb 1, 1998 · CD40-CD154-mediated contact-dependent signals between B and T cells are required for the generation of thymus dependent (TD) humoral immune responses. CD40-CD154 interactions are however also ... WebJun 16, 2024 · The MFIs of CD40 were independent from the dose of EcML, speculating that the expression of CD40 reached a saturation point even at the lowest concentration (0.625 μg/mL). ... Amanna, I.J.; Slifka, M.K. Contributions of humoral and cellular immunity to vaccine-induced protection in humans. Virology 2011, 411, 206–215. [Google Scholar] ... WebAug 27, 2006 · Huan, C., Kelly, M., Steele, R. et al. Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity. Nat Immunol 7 , 1082–1091 (2006). https ... journey t-shirts womens